Endocrine Abstracts

Testosterone levels in normally cycling women are generally assumed to be elevated during ovulation. The clinical relevance of changing testosterone levels during the menstrual cycle, however, is unclear, due to poor performance of current direct immunoassays for testosterone at low concentrations.An isotope dilution-liquid chromatography–tandem mass spectrometry (ID-LC–MS/MS) method with sufficient reliability and sensitivity1 was u...

Background: Data from several clinical studies have demonstrated the benefit of GH treatment in relation to bone mineral density and body composition in young adults who received GH treatment in childhood due to GHD1–3. There are recommendations to use a higher GH dose in the transition phase compared to the GH dose required during adulthood to mimic the endogenous GH secretion4,5.Methods: Data from NordiNet IOS have been analy...